AGCL Hemostatic Powder (Ionic Gelation Hemostatic Spray Powder)
AGCL Hemostatic Powder is a next-generation sprayable hemostatic agent designed for ultrafast bleeding control in trauma, emergency, and surgical environments. The powder is applied directly to a bleeding wound where it rapidly reacts with calcium ions present in blood, triggering the formation of a strong hydrogel barrier in approximately one second. This immediate gelation effectively seals the wound surface and stops severe bleeding almost instantly. Its sprayable format enables clinicians and first responders to treat deep, irregular, or complex wounds that may be difficult to manage with conventional dressings or patch-based hemostatic materials.
The formulation combines alginate, gellan gum, and chitosan, three naturally derived and biocompatible biomaterials that work together to create both mechanical and biochemical hemostasis. Alginate and gellan gum rapidly undergo ionic gelation when exposed to blood, forming a durable gel layer that acts as a physical barrier to blood loss. Chitosan enhances the process by interacting with blood components to accelerate clot formation and strengthen wound sealing. This synergistic action allows AGCL Hemostatic Powder to deliver rapid bleeding control while remaining safe for direct contact with human tissue.
AGCL powder features a unique three-dimensional microstructure capable of absorbing more than seven times its own weight in blood, enabling rapid management of heavy bleeding even in high-pressure hemorrhage conditions. Once gelation occurs, the hydrogel barrier exhibits strong adhesive properties with adhesion strength exceeding 40 kPa, ensuring the seal remains stable even under manual compression. This durable barrier helps maintain wound closure during the critical early moments of hemorrhage control and significantly reduces blood loss.
In addition to its rapid hemostatic action, the powder demonstrates excellent biocompatibility and antimicrobial performance. Laboratory studies show a hemolysis rate below three percent and cell viability above ninety-nine percent, indicating minimal damage to surrounding tissues. The material also offers antibacterial efficacy of up to 99.9 percent, helping reduce the risk of infection at the wound site. Beyond bleeding control, the formulation supports biological healing by promoting tissue regeneration, angiogenesis, and collagen formation, contributing to faster wound recovery and improved clinical outcomes.
AGCL Hemostatic Powder also provides practical advantages in demanding medical environments. The product remains stable for up to two years at room temperature and maintains its performance in high-humidity conditions. This durability and extended shelf life make it highly suitable for emergency medical kits, field medicine, disaster response, and remote healthcare environments where reliable bleeding control solutions must be readily available without specialized storage.
Clinical and Surgical Applications
Rapid hemorrhage control in trauma and emergency medicine
Management of deep, irregular, and complex wounds in accident and injury cases
Pre-hospital emergency care by paramedics and first responders
Battlefield and military medicine for combat casualty bleeding control
Hemostasis during general surgical procedures
Bleeding management in highly vascular organ surgeries such as liver procedures
Use in disaster response and humanitarian medical missions
Emergency bleeding control in remote or resource-limited healthcare settings
